NEXGEN® ProtectCore Vials

Advanced Protection for Sensitive Drug Formulations

Highly sensitive pharmaceutical formulations can be affected by interactions between the drug product and the container surface. Leachables may impact stability, while protein adsorption can lead to:

Denaturation
Aggregation
Reduced therapeutic effectiveness

Advanced Internal Barrier Surface

NEXGEN® ProtectCore Vials are designed to address these challenges by incorporating an advanced internal barrier surface that helps minimize interaction between the glass container and the drug formulation.

This optimized surface performance supports improved stability, particularly for sensitive drugs formulated within neutral to mildly acidic pH ranges.

Stability and Consistency

The barrier effect helps reduce the release of glass-derived ions, limiting pH variability and supporting consistent formulation performance. This is especially beneficial when reconstituting drugs using common diluents such as water for injection (WFI).

Manufactured from high-quality Type I Borosilicate Glass, NEXGEN® ProtectCore Vials provide a reliable solution for maintaining the stability, integrity, and effectiveness of sensitive pharmaceutical products.

NEXGEN® ProtectCore Vials — Reliable Storage for Sensitive and Complex Formulations

NEXGEN® ProtectCore Vials are designed to provide a stable and reliable container solution for pharmaceutical products requiring enhanced protection from glass–drug interactions.

Particularly Suitable For:

Complex protein formulations
Radiopharmaceutical products
Reconstitution diluents
Sensitive injectable therapies

The reduced release of glass-derived ions also supports the storage of formulations containing amino acids, such as parenteral nutrition solutions, helping maintain chemical stability and product integrity.

Integration and Manufacturing

Available in Ready-To-Use (RTU) configurations that are pre-washed and pre-sterilized, NEXGEN® ProtectCore Vials integrate seamlessly with a wide range of fill-and-finish systems.

Their compatibility with nested processing workflows also supports efficient handling throughout manufacturing, including lyophilization cycles when required.

Benefits

Enhanced Stability and Reduced Interaction Risk

The optimized internal surface of NEXGEN® ProtectCore Vials acts as a protective barrier, supporting drug stability and formulation integrity.

Key Advantages Include:

Reduced glass–drug interaction
Controlled ion release for improved pH stability
Lower risk of protein adsorption
Improved stability for sensitive formulations
Enhanced consistency during storage and reconstitution

These features make NEXGEN® ProtectCore Vials a dependable container choice for pharmaceutical products requiring enhanced protection and performance.

Nexgen Pharma Pack PLC

Headquarters 124-128 City Road
EC1V2NX London
Industrial address Highwork Road Swindon
SN34TZ United Kingdom
Share capital 1,300.000.00