Advanced Lyophilization Performance with Optional Light Protection
Due to stability limitations in liquid form, a significant portion of biologic therapies are supplied as lyophilized products. During freeze-drying, issues such as vial fogging can lead to increased reject rates, while incomplete residual emptying after reconstitution may require overfilling to compensate for product loss.
NEXGEN® LyoCore Vials are specifically designed to address these challenges through an advanced hydrophobic internal surface that enhances lyophilization performance.
Minimized Fogging: This optimized surface minimizes condensation and fogging during the freeze-drying cycle.
Improved Recovery: Enhances residual emptying after reconstitution.
Quality Material: Manufactured from high-quality Type I Borosilicate Glass.
NEXGEN® LyoCore Vials provide a chemically uniform internal environment that supports consistent product behavior throughout processing, storage, and administration. By improving process efficiency and product recovery, they help enhance safety, reduce waste, and optimize performance for injectable lyophilized therapies.
For formulations requiring additional light protection, NEXGEN® LyoAmber Vials extend these benefits by combining optimized lyophilization performance with integrated protection against light exposure.
Produced from Type I Borosilicate Amber Glass, NEXGEN® LyoAmber Vials shield sensitive molecules from light while maintaining the same advanced internal surface characteristics designed for efficient freeze-drying and product recovery.
Ideal for highly sensitive therapies:
Antibody–drug conjugates (ADCs)
Complex biologic products requiring both lyophilization and light protection.
Together, NEXGEN® LyoCore and NEXGEN® LyoAmber Vials provide a comprehensive container solution that ensures formulation stability, process efficiency, and compliance with pharmaceutical light-protection requirements.
NEXGEN® LyoCore Vials are designed to enhance lyophilization processes by minimizing fogging and improving residual emptying after reconstitution, supporting accurate dosing and patient safety.
Their optimized hydrophobic internal surface helps maintain clear visibility and stable product behavior during freeze-drying, addressing common challenges associated with sensitive formulations such as:
Antibody–drug conjugates (ADCs)
Biologics
Vaccines
Other high-value injectable therapies
By enabling consistent performance during high-volume production, NEXGEN® LyoCore Vials support efficient fill-and-finish operations and reliable processing across industrial manufacturing environments.
For formulations requiring additional light protection, NEXGEN® LyoAmber Vials combine the same lyophilization performance with amber glass light shielding, making them particularly suitable for photosensitive biologics and complex injectable drugs.
Both vial types are available in Ready-To-Use (RTU) configurations that are:
Pre-washed and pre-sterilized, ensuring compatibility with a wide range of filling lines.
Nested configuration supports seamless processing throughout the entire manufacturing workflow, including freeze-drying cycles.
Together, NEXGEN® LyoCore and NEXGEN® LyoAmber Vials provide a reliable container solution for lyophilized injectable products, supporting formulation stability, manufacturing efficiency, and regulatory compliance.
NEXGEN® LyoCore and NEXGEN® LyoAmber Vials combine advanced hydrophobic surface performance with high-quality Type I borosilicate glass to deliver superior reliability throughout lyophilization and reconstitution processes.
The optimized internal surface is engineered without the use of silicone, eliminating the risk of free silicone and supporting consistent product behavior during manufacturing and administration.
Hydrophobic internal surface that reduces fogging during freeze-drying
Improved residual emptying after reconstitution
Reduced risk of lyophilized cake disruption
Lower reject rates and improved cosmetic quality
Enhanced process consistency and production efficiency
Reduced risk associated with free silicone
Reliable performance for sensitive biologic and protein-based therapies
Integrated light protection for photosensitive formulations
Improved stability for complex biologics such as antibody–drug conjugates (ADCs)
Combined lyophilization performance and light shielding in a single container solution
Together, NEXGEN® LyoCore and NEXGEN® LyoAmber Vials provide a comprehensive solution for lyophilized pharmaceutical products, supporting formulation stability, process reliability, and efficient manufacturing.
Headquarters 124-128 City Road
EC1V2NX London
Industrial address Highwork Road Swindon
SN34TZ United Kingdom
Share capital 1,300.000.00
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